منابع مشابه
RGS Proteins in Heart: Brakes on the Vagus
It has been nearly a century since Otto Loewi discovered that acetylcholine (ACh) release from the vagus produces bradycardia and reduced cardiac contractility. It is now known that parasympathetic control of the heart is mediated by ACh stimulation of G(i/o)-coupled muscarinic M2 receptors, which directly activate G protein-coupled inwardly rectifying potassium (GIRK) channels via Gβγ resultin...
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Regulator of G-protein–signaling (RGS) proteins play a key role in the regulation of G-protein–coupled receptor (GPCR) signaling. The characteristic hallmark of RGS proteins is a conserved 120-aa RGS region that confers on these proteins the ability to serve as GTPase-activating proteins (GAPs) for G proteins. Most RGS proteins can serve as GAPs for multiple isoforms of G and therefore have the...
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Modelling multi-tasking behaviour is an important phase of real-time system design. It is shown how task scheduling principles can be captured in a CCS-based process algebra via extensions for both asymmetric interleaving, to model intraprocessor scheduling decisions, and for asynchronous communication, to model interprocessor precedence constraints. Examples are given of task preemption, block...
متن کاملRGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins.
The intracellular regulator of G protein signalling (RGS) proteins were first identified as GTPase activating proteins (GAPs) for heterotrimeric G proteins, however, it was later found that they can also regulate G protein-effector interactions in other ways that are still not well understood. There is increasing evidence that some of the effects of RGS proteins occur due to their ability to in...
متن کاملMulti-tasking for TinyOS
Tasks in TinyOS execute non-preemptively and run to completion, forcing programmers to keep individual tasks short and spread lengthy operations across multiple tasks – a major divergence from conventional programming paradigms. This report documents our attempt to incorporate multi-tasking into TinyOS and its subsequent effect on power consumption of “motes”. We succeeded in modifying the Tiny...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2005
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000158287.49872.4e